ABSTRACT
Background: Meningiomas account for about a third of all central nervous system tumours worldwide. Though very common, quite less is known about its epidemiology. This study aims to establish the epidemiological parameters and hormone receptor status (Progesterone Receptor-PR) involved in the development of Meningiomas.Methods: This observational study included 50 patients. Epidemiological parameters studied included age, sex, symptoms, history of hormone intake, smoking, recurrence, family history, history of other hormone related tumours and radiological assessment of tumour site. Surgical samples were grossed and typed according to the WHO standards. Immunohistochemical staining was done using PR to establish the role of hormonal receptors in the development of meningiomas.Results: The mean age was 46.84±13.54 years. The ratio of male and female (Male:Female) was 1.0:2.3. 48.5% of females had history of hormonal pill intake and 28.6% had hormone related tumours, of which fibroid was most common. Amongst the sites involved cerebral convexity was most common (56%). Chi-square (χ2) test showed that there was a significant association between histological grade and PR expression of the patients (p=0.0002).Conclusions: Positivity for hormone receptors like PR, increased intake of hormonal pills by females and association of meningioma with hormone related tumours indicates that hormonal milieu plays a significant role in the growth of meningiomasχχ. This could thus provide an insight to the pathogenesis of meningiomas. In addition, mifepristone, an anti-progestin could be a player in the medical management of meningiomas.
ABSTRACT
Background: The task of using the growth chart by Anganwadi Workers (AWWs) for growth monitoring requires technical skill. It was hypothesized that skill up-gradation can make a difference in the performance of AWWs in regard with growth monitoring. The aim of the study was to evaluate the effect of intervention in improving skill of AWWs regarding growth chart plotting and interpretation.Methods: It was a field based interventional study, which was conducted in rural areas of Varanasi district, India. A total of 66 AWWs each from Chiraigaon (intervention) and Cholapur (control) community development blocks of Varanasi district was selected for the study. Each AWW was provided 3 weight readings of different ages for plotting and 4 filled growth charts for interpretation. Chi square test has been applied to assess the significant difference.Results: Only around 10% of AWWs could correctly plot all 3 growth charts and similar proportion of AWWs could also correctly interpret all 4 filled growth charts. The planned intervention could significantly improve their skill of growth chart plotting and interpretation and during end line survey 41% and 77% of AWWs could correctly plot all 3 growth charts and interpret all the four growth charts, respectively.Conclusions: The developed hypothesis is proved, and intervention was found effective in significantly improving the skills of AWWs in regard with growth monitoring.
ABSTRACT
Epidemiological transition has given the opportunity to grow the traditional system of medicine across the world. Indian healthcare system which is already famous for providing quality of medical services at affordable cost as compared to developed countries took advantage of this opportunity and created a ‘basket of services’ by merging traditional medicines in existing allopathic system to attract patients across the borders. Government has made efforts in the direction of promoting medical tourism in the country and this has been fuelled by the private players both nationally and internationally. Recently this medical tourism has proved a major growth factor for expansion of Indian economy. However, the growth in this sector is underscored in terms of market share and cost advantages due to various challenges. There is also a need for proper diversion of revenue by a clear cut mechanism to strengthen the nation’s healthcare sector.
ABSTRACT
Background: Reproductive Tract Infections (RTIs) including Sexually Transmitted Infections (STIs) are ‘silent’ epidemics and are recognized as public health problem and rank second as the cause of healthy life lost among women of reproductive age after maternal morbidity and mortality in developing countries. Development and use of IEC material along with active participation by the community ensures delivery of appropriate information and knowledge to people which in turn empowers them to make informed decisions about their health. Methods: This was a ‘Multi-centric action research demonstration study’ to empower and engage the Self Help Groups (SHGs) women by creating awareness and sustaining interest through lesson plans in the IEC material regarding prioritized problem, required interventions and their access for syndromic recognition of the RTI/STIs. As an intervention, series of workshops were conducted with the help of pre-developed IEC material. 400 households (200 from each intervention and control sites) of SHG women were interviewed for baseline and endline each. Results: Intervention was found effective in the form of a significant improvement in the level of awareness about RTI/STI, correct knowledge about white discharge, capability to identify the symptoms of RTI/STI and health seeking behavior of the respondents. Conclusion: This study provides experience of the feasibility, efficacy and impact of health education interventions and point out that cost-effective strategies for prevention of RTI/STI are needed through information, education, and behavior change.